2 edition of Optimisation of attenuation correction for PET brain activation studies found in the catalog.
Optimisation of attenuation correction for PET brain activation studies
Written in English
Thesis (M.Sc.) - University of Surrey, 1996.
|Contributions||University of Surrey. Department of Physics.|
Fig. 2 Regions in which rCBF exhibited positive correlation with SPV of caloric nystagmus. (A) Right beating nystagmus group (group I, n = 6). 1, right inferior parietal lobule (BA 40); 2, right posterior insula; 3, pyramis of the cerebellar vermis; 4, left superior temporal gyrus (temporal pole: BA 38); 5, left cerebellar correlation foci in the right middle frontal gyrus (BA 6. Lastly, a general problem is the large intersubject variability in TSPO expression, which is shown in this and other PET studies. 14–16 To correct this variability, normalization to whole-brain.
Hongyu An, PhD, Washington University presented A multi-centre evaluation of eleven clinically feasible brain PET/MRI attenuation correction techniques using a large cohort of patients (Ladefoged CN, Law I, Anazodo U, St Lawrence K, Izquierdo-Garcia D, Catana C, Burgos N, Cardoso MJ, Ourselin S, Hutton B, Mérida I, Costes N, Hammers A, Benoit. CT-based attenuation correction and related artefacts. A typical whole-body PET scan is started 60 min after the intravenous administration of ± MBq 18 F-FDG per kg body weight. The axial field of view of the PET system (10–15 cm) is extended by imaging in multiple bed positions to cover the whole body acquisition time of 4–6 min per bed position produces images of relatively good.
Magnetic resonance imaging-only radiotherapy treatment planning (MRI-only RTP) and positron emission tomography (PET)–MRI imaging require generation of synthetic computed tomography (sCT) images from MRI images. In this study, initial dosimetric evaluation was performed for a previously developed MRI-based attenuation correction (MRAC) method for use in MRI-only RTP of the brain. The latter included brain, torso, prostate and phantoms. The contributions geometric and/or dosimetric performance metrics were also noted. The majority of studies are carried out on the brain for 5–10 patients with PET/MR applications in mind using a voxel based method. T1 weighted images are most commonly applied.
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Simultaneous positron emission tomography (PET)/magnetic resonance (MR) imaging has been Optimisation of attenuation correction for PET brain activation studies book to combine the soft-tissue contrast of MR imaging with the molecular sensitivity and specificity of PET.
However, a remaining challenge lies in obtaining a reliable photon attenuation correction (AC) map, which is crucial for accurate PET Cited by: Objectives Generally, in patients with nervous system diseases undergoing brain PET/CT imaging, they also have enhanced MRI or enhanced CT so that the CT images in PET/CT scan is used only for Attenuation Correction(AC).
The aim of this study was to reduce unnecessary patient radiation doses from the CT portion of PET/CT and determine the minimum CT acquisition parameters that can Author: Jung Sun Kim, Ho Sung Kim, Jae Kwang Ryu, Woo Young Jung, Kyeong Rae Dong, Woon Kwan Chung.
PET (positron emission tomography) biokinetic modelling relies on accurate quantitative data. One of the main corrections required in PET imaging to obtain high quantitative accuracy is tissue attenuation correction (AC). Incorrect non-uniform PET-AC may result in local bias in the emission images, and thus in relative activity distributions and time activity curves for different Cited by: 1.
The failure to compensate for subject motion between attenuation correction scans and emission scans precludes the optimization of functional brain imaging techniques.
We have developed an automated method for attenuation correction that compensates for subject motion by deriving each set of correction factors from the corresponding emission by: CT protocol intents used in PET/CT. According to all the 27 considered studies, a CT scan in PET/CT exams can be done for different purposes.
In Table 5, we identified and reported 5 classes of protocol intents: (A) CT acquisition for anatomic localization and attenuation correction, (B) CT acquisition for attenuation correction only (ULTRA-low dose), (C) CT acquisition for diagnostic Cited by: 2.
Table 1 summarizes the patient demographics of the clinical 18 F-FDG PET brain studies. PET data acquisition started 31 ± 5 min post-injection and lasted 20 min. Low-dose CT scanning for attenuation correction (kVp =mAs = 20, rotation speed = s and voxel size = 1 × 1 × mm 3) preceded PET data acquisition.
PET raw data were. Keywords: attenuation correction, Dixon and ZTE MR, deep neural network, brain PET imaging, PET/MR Abstract Positron emission tomography (PET) is a functional imaging modality widely used in neuroscience studies.
To obtain meaningful quantitative results from PET images, attenuation correction is necessary during image reconstruction. We evaluated the accuracy of PET attenuation correction using our method in the context of FDG PET/CT brain scans.
The PCT images showed an average MAE of ± HU, average correlation coefficient of ± and average DCS larger than for. Distribution of DLP 75kg according to system number and clinical purpose for PET/CT oncology whole body (Data submissions from a system for more than one clinical purpose are labelled with a letter suffix) (a), PET/CT infection/inflammation (b), PET/CT brain (Mean DLP data (not weight-derived) normalised to a cm CTDI phantom are given for PET/CT brain; Data submissions from a.
Objective. Pharmacologic approaches to study brown adipocyte activation in vivo with a potential of being translational to humans are desired. The aim of this study was to examine pre- and postsynaptic targeting of adrenergic system for enhancing brown adipose tissue (BAT) metabolism quantifiable by [18 F]fluorodeoxyglucose ([18 F]FDG) positron emission tomography (PET)/computed tomography.
Burgos N, Cardoso MJ, Thielemans K, Modat M, Pedemonte S, Dickson J, et al. Attenuation correction synthesis for hybrid PET-MR scanners: application to brain studies. IEEE Trans Med Imaging. ;33(12)– The combination of functional and anatomical imaging technologies such as Positron Emission Tomography (PET) and Computed Tomography (CT) has shown its value in the preclinical and clinical fields.
In PET/CT hybrid acquisition systems, CT-derived attenuation maps enable a more accurate PET reconstruction. Attenuation Correction for Brain PET Imaging Using Deep Neural Network Based on Dixon and ZTE MR Images2 alBerker et alLadefoged et alSekine et alLeynes et alKhalif e et alYang et al ).
Another category relies on the atlas generated from prior patients’ CT and MR pairs. The attenuation correction method has been evaluated with brain CT, MRI and PET data from the brain PET-SORTEO database.
Figure 2 shows the result from the brain images. Visual inspection shows that the corrected PET image has bright signals at the center of the brain compared to a relatively dark region on the uncorrected image. van der Doef TF, Doorduin J, van Berckel BNM, Cervenka S.
Assessing brain immune activation in psychiatric disorders: clinical and preclinical PET imaging studies of. Then applying a pre-filtering on both PET and CT images before segmentation of structures in order to reduce the respiratory related attenuation correction artifacts of PET emission data.
Partial-volume effects generally result in an underestimation of tumor tracer uptake on PET-CT for small lesions, necessitating partial-volume correction (PVC) for accurate quantification.
However, investigation of PVC in dynamic oncological PET studies to date is scarce. The aim of this study was to investigate PVC’s impact on tumor kinetic parameter estimation from dynamic PET-CT.
Positron Emission Tomography and Computed Tomography / MRI is the combination of functional imaging as well as anatomical imaging. PET in Brain DisordersPET in Brain Disorders Simultaneous PET/MRI study in Alzheimer disease and MRI-based PET attenuation correction, as well as encouraging clinical and specifically preclinical PET/MRI.
Attenuation correction for freely moving small animal brain PET studies based on a virtual scanner geometry. Physics in Medicine and Biology, 59(19), [More Information].
Purchase Quantitative Functional Brain Imaging with Positron Emission Tomography - 1st Edition. Print Book & E-Book. ISBN. 25 Montgomery AJ, Thielemans K, Mehta MA, et al.: Correction of head movement on PET studies: comparison of methods.
J Nucl Med ; –Medline, Google Scholar. 26 Rizzo G, Veronese M, Tonietto M, et al.: Kinetic modeling without accounting for the vascular component impairs the quantification of [lsqb]11C[rsqb]PBR28 brain PET data.Visiting Graduate Students.
Yajing Zhang (Fall ), Delivery and Analysis of NPB4-coated PLGA Brain-penetration Nanoparticles using PET imaging. Hui Liu (Fall ), Attenuation correction and partial volume correction of the cardiac imaging in dedicated SPECT studies.
Peng Fan (Fall ), Scatter and crosstalk correction for simultaneous dual-isotope dynamic SPECT using CZT.rection of PET images from non-attenuated corrected PET images using deep direct attenuation correction (Deep-DAC) to achieve quantitative brain PET images. Unlike other deep learning–based methods, the proposed method in the current study does not require anatomical information from CT or MRI.
As such, it holds potential value given that cross.